G protein-coupled receptors
Blocking Them All: β-Arrestins Inhibit Cellular Signaling
01/10/2008
β-arrestins are scaffold proteins that link G
protein-coupled receptors to multiple “nonclassical”
signaling pathways. In this issue of Molecular Cell,
Mo et al., 2008 show that
β-arrestin1 also switches off signaling through
the STAT1 transcription factor, thereby
inhibiting interferon-induced antiviral
responses.
Molecular Cell, Vol 31, 619-621, 05 September 2008
Molecular Cell, Vol 31, 619-621, 05 September 2008
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