health effect
Bisphenol A and Risk of Metabolic Disorders
16/09/2008
In this issue of JAMA, Lang and colleagues1 report
the results of the first major epidemiologic study to
examine the health effects associated with the
ubiquitous estrogenic chemical bisphenol A (BPA).
This compound is the base chemical (monomer) used to
make polycarbonate plastic food and beverage
containers, the resin lining of cans, and dental
sealants; it also is found in "carbonless" paper used
for receipts as well as a wide range of other common
household products. Based on their analysis of data
from the National Health and Nutrition Examination
Survey 2003-2004, Lang et al report a significant
relationship between urine concentrations of BPA and
cardiovascular disease, type 2 diabetes, and
liver-enzyme abnormalities in a representative sample
of the adult US population. This report, suggesting
links between BPA and some of the most significant
and economically burdensome human diseases, is based
. . .
JAMA. 2008;300(11):1353-1355. Published online September 16, 2008 (doi:10.1001/jama.300.11.1353)
JAMA. 2008;300(11):1353-1355. Published online September 16, 2008 (doi:10.1001/jama.300.11.1353)
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